The effect of endotracheal administration of N-acetylcysteine and heparin on symptom improvement in acute respiratory distress

The effect of endotracheal administration of N-acetylcysteine and heparin on symptom improvement in acute respiratory distress syndrom and lung contusion

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190205042631N1

Enrollment

Registered

2019-02-28

Start date

2019-02-20

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung disorder. Respiratory disorder, unspecified

Interventions

Intervention 1: Intervention group: receive 500 units of heparin every four hours and 200 mg of acetylcysteine dissolved in 10 mililitr every 4 hours by intratracial for 7days. Intervention 2: Control

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with acute respiratory distress syndrom and lung cantusion

Exclusion criteria

Exclusion criteria: Pregnancy Allergy to heparin or acetylcysteine Active bleeding

Design outcomes

Primary

Measure	Time frame
Improvement of respiratory symptoms. Timepoint: After seven days. Method of measurement: Checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Rouhi

Shahre-kord University of Medical Sciences

hamidroohi@skums.ac.ir+98 38 3222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026