ischemic hypoxic episma encephalopathy.
Conditions
Interventions
Intervention 1: Intervention group: Infants with moderate to severe HIE. Intervention 2: Control group: Infants with moderate to severe HIE with conventional treatment.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 30 Days
Inclusion criteria
Inclusion criteria: Apgar score less than 5 in 10 minutes after the birth or need of the baby to continue the regenerative process (including ventilation with mask and intubation) until 10 minutes after birth or acidosis in the first hour after birth (PH in umbilical cord or arterial blood and Or capillary blood less than 7) or a base deficiency greater than 16 millimoles / liter in any of the blood samples within 60 minutes of the first birth Clinical manifestations of moderate to severe postpartum encephalopathy
Exclusion criteria
Exclusion criteria: Parental dissatisfaction at each stage of induction cooled therapy The infant's center temperature reaches more than 38 degrees Celsius Neonatal abnormalities require surgery Newborns with obvious anomalies require immediate intervention such as cyanatoid heart disease In case of possible complications of treatment, a newborn resuscitation, such as severe bradycardia associated with apnea
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infants with moderate to severe HIE. Timepoint: Duration 48 to 72 hours of birth. Method of measurement: Clinical-Biochemical. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMojtaba Adineh
Mashhad University of Medical Sciences
Outcome results
None listed