supratentorial brain tumor. Benign neoplasm of brain, supratentorial
Conditions
Interventions
Intervention 1: Intervention group: In group A, after induction of general anesthesia and before incision of the skin, a dose of 20 mg / kg of transamic acid is injected after the initial loading dose
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: All surgeries for supratentorial tumors Age over 16 years Discontinue drugs that cause coagulation disorders Women in non-pregnant status
Exclusion criteria
Exclusion criteria: history of coagulation disorders history of gastrointestinal disease history of liver disease history of heart disease history of renal failure (creatinine clearance less than 70min / mL, oliguria or dialysis 28 days before surgery) history of diabetes history of hypersensitivity disorders to ibuprofen, aspirin, nonsteroidal anti-inflammatory drugs, COX-2 inhibitors history of asthma long-term use of anticonvulsant drugs smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematocrit. Timepoint: Before surgery and one day after surgery. Method of measurement: Blood sampling.;Bleeding volume. Timepoint: during surgery. Method of measurement: Direct and visual measurement. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Bashir Mirtajani
Shahid Beheshti University of Medical Sciences
Outcome results
None listed