The effect of oral Gabapentin on sedative consumption in mechanically ventilated patients in intensive care unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190202042588N1

Enrollment

Registered

2019-04-28

Start date

2019-05-01

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dependence on respirator [ventilator] status. Dependence on respirator [ventilator] status

Interventions

Intervention 1: Intervention group: In this group, the fixed dose of Gabapentin (300mg TDS, daily) dissolved in 5cc normal saline is administered through nasogastric tube , and then, if necessary, wi

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age should be ove18 years of age. 2. Mechanical ventilation for more than 3 days

Exclusion criteria

Exclusion criteria: 1. Renal failure. 2. Acute neurological disease and Neuromuscular disease. 3. Unstable Hemodynamic

Design outcomes

Primary

Measure	Time frame
Fentanyl consumption. Timepoint: daily. Method of measurement: microgram/kilogram/hour.;Midazolam consumption. Timepoint: Daily. Method of measurement: milligram/kilogram.;Gabapentin prescribed dosage. Timepoint: Daily. Method of measurement: milligram.	—

Secondary

Measure	Time frame
Number of days under ventilation. Timepoint: Daily. Method of measurement: Nursing Report.;Ramsay scale score. Timepoint: hourly. Method of measurement: Scale Score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Salarian

Shahid Beheshti University of Medical Sciences

sarasalarian@sbmu.ac.ir+98 21 7755 8001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026