Comparing the effect of acetaminophen and ibuprofen in reducing the pain of venipuncture

Comparison of the effect of acetaminophen syrup with oral ibuprofen in reducing pain caused by peripheral vascularization in children with acute lymphoblastic leukemia.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190202042583N5

Enrollment

Registered

2023-11-11

Start date

2023-11-22

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lymphoblastic leukemia. Acute lymphoblastic leukemia [ALL]

Interventions

Intervention 1: Intervention group: prescription of acetaminophen syrup with 15mg/kg dosing, once, taken orally 1hour before needle insertion. Intervention 2: Intervention group: prescription of Ibupr

Eligibility

Sex/Gender

All

Age

3 Years to 12 Years

Inclusion criteria

Inclusion criteria: All Children between 3-12 years old diagnosed with ALL came for Chemotherapy

Exclusion criteria

Exclusion criteria: People younger than 3 years old and older than 12 years old Neutrophil < 1500 Alergic history of Acetaminophen/ Ibuprofen Plt<50,000 Fever & Nausia/ Vomitting Hb < 8g/litre Hepatic disfunction

Design outcomes

Primary

Measure	Time frame
Drug effects on pain reduction during IV needle insertion. Timepoint: Pain reduction of needle insertion 60 minutes after oral taking of drugs. Method of measurement: Ouches pain scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Naderisorki

Mazandaran University of Medical Sciences

Dr.naderisorki@gmail.com+98 11 3334 3011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026