Acute Lymphoblastic Leukemia. Acute lymphoblastic leukemia [ALL]
Conditions
Interventions
Intervention 1: Intervention group: Each patient is evaluated for the presence and severity of mucositis before receiving the drug by the dentist. For the patient, mouthwashWhich is performed every 8
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 15 Years
Inclusion criteria
Inclusion criteria: Age between 5 to 15 years old Acute Lymphoblastic Leukemia under the treatment of Children's Oncology Group (COG) chemotherapy protocol High dose of methotrexate No mucositis before receiving methotrexate No nausea and vomiting before starting methotrexate Platelet count above 100,000 per µl before From the onset of methotrexate The absolute neutrophil count exceeds 1500 ml / µl before starting methotrexate Hemoglobin above 8 g / l Before starting methotrexate, the ability to use mouthwash for 30 seconds every 8 hours
Exclusion criteria
Exclusion criteria: Presence of fever Use of systemic or topical antibiotics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Mucositis. Timepoint: Before receiving the drug and re-day four after the onset of methotrexate. Method of measurement: By the dentist and according to the Criteria WHO.;Periods of Mucositis. Timepoint: Before receiving the drug and re-day four after the onset of methotrexate. Method of measurement: By the dentist and according to the Criteria WHO. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Naderisorki
Mazandaran University of Medical Sciences
Outcome results
None listed