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The therapeutic effect of Sildenafil Citrate on maternal and fetal outcomes of pregnancies associated with severe preeclampsia

The therapeutic effect of Sildenafil Citrate on maternal and fetal outcomes of pregnancies associated with severe preeclampsia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190201042577N1
Enrollment
64
Registered
2019-03-07
Start date
2019-01-19
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Preeclampsia. Severe pre-eclampsia

Interventions

Intervention 1: Intervention group: receive sildenafil tablets 25 mg every 8 hours. Intervention 2: Control group: receive a tablet of the same color and shape as the sildenafil tablet every 8 hours.

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Pregnant women with single pregnancy with gestational age 24 to 34 weeks Ladies 18 to 50 years old Patients with the diagnosis of severe preeclampsia (systolic blood pressure greater than 160 and diastolic blood pressure greater than 110 in two times with a minimum measurement time of 4 hours and proteinuria greater than 300 mg in 24 hours) indicating an expected treatment.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The mean of the pregnancy period since the diagnosis of severe preeclampsia until the end of pregnancy. Timepoint: since the diagnosis of severe preeclampsia until the end of pregnancy. Method of measurement: day.

Secondary

MeasureTime frame
Mean maternal blood pressure. Timepoint: Every four hours. Method of measurement: mercury Barometer.;Newborn birth weight. Timepoint: at birth. Method of measurement: scaler.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Kamkar

Mashhad University of Medical Sciences

Kamkara951@mums.ac.ir+98 51 3611 1357

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026