Evaluation of the effect of ginger supplementation on clinical outcomes, serum levels of some inflammatory markers, TAC and expression of mir-21 in patients with active ulcerative colitis

Evaluation of the effect of ginger supplementation on clinical outcomes, serum levels of some inflammatory markers(TNF-a, hs-CRP) , TAC and expression of mir-21 in patients with active ulcerative colitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190129042552N1

Enrollment

Registered

2019-06-21

Start date

2019-06-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis. Ulcerative colitis

Interventions

Intervention 1: Intervention group: ginger supplementation 3 grams per day for 3 months. Intervention 2: Control group: placebo supplementation 3 grams daily for 3 months.

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Moderate to sever active ulcerative colitis patients Absence of fulminant colitis Male and female aged 18 to 50 years Body mass index 18/5 - 30 Lack of other digestive disorders and uncontrolled disease Lack of sensitivity to ginger

Exclusion criteria

Exclusion criteria: Use of anti TNF-a Pregnancy Menopause Use of anti-coagulants, anti-diabetic and anti-blood pressure medication

Design outcomes

Primary

Measure	Time frame
Clinical score. Timepoint: Before and after intervention. Method of measurement: Partial mayo score.;Serum level of mir-21. Timepoint: Before and after intervention. Method of measurement: PCR.;Serum level of TNF-a. Timepoint: Before and after intervention. Method of measurement: Elisa kit.	—

Secondary

Measure	Time frame
Serum level of hs-CRP. Timepoint: Before and after intervention. Method of measurement: Elisa kit.;Total antioxidant capacity. Timepoint: Before and after intervention. Method of measurement: Elisa kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForough shayesteh

Ahvaz University of Medical Sciences

Forough_shayesteh@yahoo.com+98 61 3333 3477

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 28, 2026