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investigate efficacy of fibrinogen blood level correction and bleeding valume in traumatic brain injury

investigate efficacy of fibrinogen blood level correction between 1.5 - 2 gr/lit to above 2 gr/lit with bleeding rate during operation and post operation hospital course in traumatic brain injury

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190129042541N1
Enrollment
30
Registered
2019-02-13
Start date
2019-03-21
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intra cranial bleeding in traumatic brain injury. Intracranial injury

Interventions

Intervention group: pre operation or during surgery intra venous fibrinogen injection was down patient. , if serum fibrinogen level is between 175 to 200 mg per lit, one gram fibrinogen was injected ,

Sponsors

vice chancellor of research . shiraz university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients who are older than sixteen years and brought to Emtiaz hospital ER, affiliated to Shiraz Univercity of medical sciemces,Shiraz, Iran, between March 2019 to March 2020 and underwent skull craniotomy whom fibrinogen level is between 1.5 to 2.0 gr/lit are include in our study

Exclusion criteria

Exclusion criteria: patients who have coagulopathy in lab data such as abnormal PTwe exclude the patients who have coagulopathy in lab data such as abnormal PT,PTT,INR, platelets counts or history of coagulopathy disorders or underwent another major surgery from other services in this admission before skull craniotomy surgery from our study

Design outcomes

Primary

MeasureTime frame
Blood volume rate. Timepoint: pre operatio and post operation. Method of measurement: blood volume messurment during operation and in hemovac and post operatin, blood volume messurment in pre and post operation CT scan.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Niakan

Shiraz University of Medical Sciences

aniakan@sums.ac.ir+98 71 3625 4206

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026