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Effect of Topical Pistacia Atlantica Oil on some Clinical symptoms of Knee Osteoarthritis

Effect of Topical Pistacia Atlantica Oil on some Clinical of Knee Osteoarthritis: a Randomized and Double Blind Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190128042525N7
Enrollment
50
Registered
2024-11-01
Start date
2024-10-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group A: Group A will use piroxicam gel topically. The duration of treatment is 3 months and twice a day. In addition, patients will be allowed to use oral analgesics drug

Sponsors

Rafsanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 50-70 The diagnosis of knee osteoarthritis is based on the criteria of the American College of Rheumatology, which is confirmed by a rheumatology specialist. The presence of average knee pain during 24 hours based on the linear-visual pain scale (VAS) between 4 and 7 cm.

Exclusion criteria

Exclusion criteria: Patients suffering from inflammatory diseases (such as lupus, rheumatoid arthritis, history of brucellosis, etc.) Cancer or serious diseases, symptoms or history of liver or kidney failure, Taking oral corticosteroids during the last 4 weeks corticosteroids injection in the last 6 months. fever Consuming medicinal plants continuously Allergy to the Pistacia Atlantica unwillingness to continue participating in the stud Failure to comply with the study protocol Observing any side effects that the patient thinks are caused Pistacia Atlantica by oil.

Design outcomes

Primary

MeasureTime frame
Knee pain intensity. Timepoint: At the beginning and the end of the study (three months after the beginning of the study). Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Bazmandegan

Rafsanjan University of Medical Sciences

clinical.research@rums.ac.ir+98 34 3428 0185

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026