mastalgia. mastalgia
Conditions
Interventions
Intervention 1: Intervention Group 1: " will be receiving tamoxifen with a dose of 10 mg / day manufactured by Iran Hormones". Intervention 2: Intervention group 2: "will be receiving fluoxetine 20 mg
Sponsors
Rafsanjan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Written consent The person must remain in the region at least during the follow-up in the region Reproductive ages between 18 to 50 years Pre-menopause, mastalgia without obvious pathologic reason The minimum score of the visual scale of pain is three
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding or a decision to have a pregnancy Contraindication of the use of the drugs mentioned (tamoxifen: pregnancy and lactation) Thromboembolic / fluoxetine disorders: severe renal and hepatic failure Patients with epilepsy who have uncontrolled seizures History of breast cancer in self or first-degree relatives A large lesion in the breast that needs surgery Suspect of any malignancy Galactorrhea History of previous surgery Hormone Therapy in the last three months Taking Oral contraceptive pill History of taking medication to treat breast pain Any mental and psychiatric illness is associated with the use of related medications Taking some medications (dopamine antagonists , Monoamine Oxidase Inhibitors (MAO), Warfarin, theophylline, hypnotics and progesterone) Irregular menstruation History of thromboembolism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure pain. Timepoint: 4 weeks, 8 weeks and 12 weeks. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of illness. Timepoint: 3 months. Method of measurement: visual analogue scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGholamreza Bazmandegan
Rafsanjan University of Medical Sciences
Outcome results
None listed