Morbid Obesity. Morbid (severe) obesity due to excess calories
Conditions
Interventions
Intervention 1: Intervention group: substance name is silymarin(milk thistle).Chemical form is C25H22O10. Capsule is 140 mg identify liver gol. patients will eat one capsule every 8 hours for four wee
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patient with morbid obesity(BMI>40 or BMI>35 with comorbidity 18 to 60 years old patient
Exclusion criteria
Exclusion criteria: Patients who are not willing to attend the study Patients are taking omega 3 pearl. Patients who have allergy to any herbal drugs Patients should to use warfarin or midazolam . Patients are doing sever physical activity. Patients use alcohol Patients who had low or very low calorie diet. Patients use distillates such as chicory or milk thistle Patients who have cirrhosis or hepatitis. Patients who have ALT more than 5 fold increase in normal level(7-56 units)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean of liver size. Timepoint: Liver measurement at first of study and after finalization of silymarin(1 month). Method of measurement: With sonography to mm.;Mean of fatty liver grade. Timepoint: Fatty liver grade at first of study and after finalization of silymarin(1 month). Method of measurement: Sonography.;Mean of Liver function test. Timepoint: Liver function test measurement at first of study and after finalization of silymarin(1 month). Method of measurement: Laboratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamed Atarodi
Iran University of Medical Sciences
Outcome results
None listed