Preventive effect of intramuscular ketamine and methadone on pain

Preventive effect of intramuscular ketamine and methadone on pain after laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190127042511N1

Enrollment

Registered

2019-12-13

Start date

2016-01-21

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain control after cholecystectomy Surgery. Cholelithiasis

Interventions

Intervention 1: Intervention group 1: One Intramuscular injection of 1.5mg per kg from 5 % Solution(50 mg in 1 ml) ketamin(Rotexmed co) before incision.injection site : deltoid muscle. Intervention 2

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: candidates for laparoscopic cholecystectomy ASA(American Society of Anesthesiologists) 1 or 2

Exclusion criteria

Exclusion criteria: Patients with a history of addiction to benzodiazepines or narcotics, including methadone

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: 5 min. Method of measurement: Visual analog scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza khalili

Esfahan University of Medical Sciences

khalili@med.mui.ac.ir+98 31 3669 4561

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026