Effect of a poly herbal mouthwash in prevention of mucositis

Efficacy of a poly herbal mouthwash in prevention of head and neck radiotherapy-induced-oral mucositis: A double-blind randomized placebo-controlled trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190123042475N2

Enrollment

Registered

2019-07-26

Start date

2019-04-21

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral mucositis. Oral mucositis (ulcerative)

Interventions

Intervention 1: Intervention group 1: poly herbal mouthwash containing Aloe vera gel 3%, Chamomile extract 1%, honey 1.5%, oil mint 1%, will be formulated in pharmacy faculty of Mashhad. All prepare

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients over the age of 18 undergoing radiotherapy

Exclusion criteria

Exclusion criteria: co-existing systemic diseases

Design outcomes

Primary

Measure	Time frame
Clinical manifestations of mucositis. Timepoint: In the beginning of the study (before the onset of intervention), 1,2,3,4,5,6,7,8 weeks after commencing oral intake of poly herbal mouthwash. Method of measurement: Clinical Examination.;Severity of mucositis based on the WHO benchmark. Timepoint: In the beginning of the study (before the onset of intervention), 1,2,3,4,5,6,7,8 weeks after commencing oral intake of poly herbal mouthwash. Method of measurement: World Health Organization classification system.	—

Measure

Time frame

Clinical manifestations of mucositis. Timepoint: In the beginning of the study (before the onset of intervention), 1,2,3,4,5,6,7,8 weeks after commencing oral intake of poly herbal mouthwash. Method of measurement: Clinical Examination.;Severity of mucositis based on the WHO benchmark. Timepoint: In the beginning of the study (before the onset of intervention), 1,2,3,4,5,6,7,8 weeks after commencing oral intake of poly herbal mouthwash. Method of measurement: World Health Organization classification system.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh Sahebnasagh

Bojnourd University of Medical Sciences

Marzieh.saheb@gmail.com+98 58 3272 8568

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026