Chronic obstructive pulmonary disease. Other chronic obstructive pulmonary disease
Conditions
Interventions
Intervention 1: Intervention group: Salmeterol spray will be used three times a day with a dose of 25 micrograms for 15 days. Intervention 2: Intervention group: A thiotropium bromide capsule is given
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with acute exacerbation of COPD Age over 35 years Spirometry or previous histories consistent with chronic obstructive pulmonary disease Patients reporting at least 10 packets of cigarette smoking
Exclusion criteria
Exclusion criteria: Acute coronary syndrome Severe associated comorbidities (cardiac and renal) Patients with a recent history of myocardial infarction Patients with prostate hypertrophy and closed glaucoma Patients with allergic rhinitis or atopy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dyspnea in daily living. Timepoint: At the beginning of the study and 15 days after the start of treatment. Method of measurement: The modified Medical Research Council scale.;Severity of chronic obstructive pulmonary disease. Timepoint: At the beginning of the study and 15 days after the start of treatment. Method of measurement: Chronic obstructive pulmonary disease assessment Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial blood gas parameters. Timepoint: At the beginning of the study and 15 days after the start of treatment. Method of measurement: Arterial blood gases. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadAli Saba
Kashan University of Medical Sciences
Outcome results
None listed