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The Effect of Grape Seed Extract Supplementation on Fasting Blood Sugar Status, Insulin Resistance and Lipid Profile in Women with Polycystic Ovary Syndrome

The Effect of Grape Seed Extract (GSE) Supplementation on Fasting Blood Sugar Status, Insulin Resistance and Lipid Profile in Women with Polycystic Ovary Syndrome (PCOS)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190122042458N1
Enrollment
50
Registered
2019-09-04
Start date
2019-07-11
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome(PCOS). Newborn light for gestational age, 2000-2499 grams

Interventions

Intervention 1: Intervention Group: Includes 25 Patients Who Will be Randomly Selected and Treated With Placebo Orally For Two Months. Intervention 2: Control Group: Includes 25 Patients Who Will be T

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age of Admission 25 to 60 Years Body Mass Index Less than or Equal to 30 Diagnosis of Women with Polycystic Ovarian Syndrome Defined as Presence of 2 Characteristics of the Following 3 Characteristics: Oligoavulation or non Ovulation, Biochemical and / or Clinical Evidence of Hyperandrogenism, Features of Transvaginal Ultrasonography Representing More than 12 Immature Follicles Less than 10 mm Per Ovary

Exclusion criteria

Exclusion criteria: Unwillingness of Patients to Participate in the Study Kidney Disease, Coronary Arteries, Acute and Chronic Pulmonary Inflammation, Short Stomach and Intestine Syndrome, Allergies Pregnancy and Lactation Traveling for More than 2 Weeks Smokers Use of Food Supplements Anti-Inflammatory Drugs Use of any Antioxidant Supplement in the Last 3 Months Use of Immunosuppressive Drugs Follow Certain Diets Change the Diet or Decide to Lose Weight

Design outcomes

Primary

MeasureTime frame
HDL. Timepoint: 0-60. Method of measurement: Laboratory Kits.;LDL. Timepoint: 0-60. Method of measurement: Laboratory Kits.;T.G. Timepoint: 0-60. Method of measurement: Laboratory Kits.;FBS. Timepoint: 0-60. Method of measurement: Laboratory Kits.;Insulin resistance. Timepoint: 0-60. Method of measurement: Laboratory Kits.;Insulin. Timepoint: 0-60. Method of measurement: Laboratory Kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPegah Sedighii

Ahvaz University of Medical Sciences

Amiraryan89@yahoo.com+98 21 3360 5280

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026