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Evaluating the efficacy of Erythropoietin and Intravenous Iron on transfusion requirements in patients undergoing cardiac surgery

Evaluating the efficacy of Erythropoietin and Intravenous Iron on transfusion requirements in patients undergoing cardiac surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190121042447N1
Enrollment
154
Registered
2019-11-23
Start date
2019-05-04
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

iron deficiency anemia.

Interventions

Intervention 1: Intervention group: 77 patients with iron deficiency anemia give 100unit/kg erythropoeitin IV bolus with 200 mg iron sucrose in 200 ml normal salin iv infusion in 1 hours. Interventio

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: patient over 18 years old CABG candidate if hemoglobin concentration less than 12 g/dl in women and less than 13 g/dl in men 1-ferritin 5 mg/l

Exclusion criteria

Exclusion criteria: Patients with uncontrolled hypertension (BP>180/110) -platelet count more than 450,000/mm3 history of thromboembolism, history of seizure, history of malignant disease liver dysfunction(transaminase>3ULN), confirmed renal impairment (serum creatinine[Cr]2 mg/dl), aplastic anemia hypersensitivity to iron history of erythropoeitin use

Design outcomes

Primary

MeasureTime frame
Transfusion requirement. Timepoint: before surgery until seven days after surgery. Method of measurement: transfused volume in mili litre.

Secondary

MeasureTime frame
Hemoglobin concentration changes. Timepoint: before surgery until seven days after surgery. Method of measurement: labaratory data in mg/dl.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactshima jafari

Tehran University of Medical Sciences

shima.jafariy@gmail.com+98 21 8802 9600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026