Compare effects propofol and dexmedetomidine in hemodynamic Changes and delirium in trauma patients in the ICU of Ali Ebn Abitaleb Hospital of Rafsanjani years 2023

Compare effects propofol and dexmedetomidine in hemodynamic Changes and delirium in trauma patients in the ICU

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190117042390N2

Enrollment

Registered

2023-10-12

Start date

2022-09-16

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: head trauma patients. Condition 2: thorax trouma. ????? ?? ?? ?????? ???? ????

Interventions

Intervention group:Two groups of 20 people receiving dexmedetomidine and propofol.

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: The entry criteria for the study, including all people with trauma in the ICU, and the age range of 18-55 years and the presence of a companion, will be considered as the entry criteria. They are distributed randomly

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
Hemodynamic changes and delirium. Timepoint: 16-12-24-48 hours after starting the drug. Method of measurement: questionnaire.	—

Primary

Measure	Time frame
Hemodynamic changes and delirium. Timepoint: 3 months. Method of measurement: This study is a clinical trial study that will be conducted on 40 trauma patients with an age range of 18-55 years, divided into two groups, that is, under anesthesia with propofol and under anesthesia with dexmedetomidine. In the end, 20 people from each group will be tested for a total of 40 people. Considering the first type error of 5% and the power of 80% and the ability to show the average difference between the two groups that is statistically significant (size effect = 0.5), 20 cases were considered for each group.	—

Measure

Time frame

Hemodynamic changes and delirium. Timepoint: 3 months. Method of measurement: This study is a clinical trial study that will be conducted on 40 trauma patients with an age range of 18-55 years, divided into two groups, that is, under anesthesia with propofol and under anesthesia with dexmedetomidine. In the end, 20 people from each group will be tested for a total of 40 people. Considering the first type error of 5% and the power of 80% and the ability to show the average difference between the two groups that is statistically significant (size effect = 0.5), 20 cases were considered for each group.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Hamid Pakzad

Rafsanjan University of Medical Sciences

pakzadmoghadam@gmail.com+98 34 3428 0042

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026