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Comparison of the effect of Hyoscine N-Butylbromide on the propofol injection pain

Comparison of the effect of Hyoscine N-Butylbromide and Lidocaine 2% on the propofol injection pain

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190109042309N2
Enrollment
80
Registered
2019-05-18
Start date
2019-02-20
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain caused by injection of propofol.

Interventions

Intervention 1: Intervention group: Propofol injection after 30 seconds of 20 mg Hyoscine. Intervention 2: Control group: Propofol injection after 60 seconds of 2% lidocaine injection at 40 mg.

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patient is a candidate for general anesthetic and surgery ages 18and 65 Ability to communicate with the research team Having at least a fifth grade of elementary school American Society of Anesthesiology Class I, II patient has the consent and willingness to participate in the research

Exclusion criteria

Exclusion criteria: Addiction Sensitive to the drugs studied Pregnancy Having Nervous-Muscular Diseases Having heart disease and history of seizures Having metabolic and gastrointestinal disorders Severe nervous and psychiatric disorders Need for induction of anesthesia and rapid intubation Kidney disease in the final stage Liver disorders

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: At the time of induction of anesthesia. Method of measurement: Assessment of Pain Scores of 4-point Verbal Rating Scale (VRS) during Injection of Propofol.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohreh Mohamadzadeh Tabrizi

Sabzevar University of Medical Sciences

mohammadzadehz@medsab.ac.ir+98 51 4401 8329

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026