Comparison of the effect of two drugs Levetiracetam and Na-valproate in the treatment of generalized tonic clonic seizures

Comparison of the effect of two drugs Levetiracetam and Na-valproate in the treatment of generalized tonic clonic seizures in children aged 5-13 years old admitted to Amirkola Hospital

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190108042287N1

Enrollment

Registered

2019-02-16

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy. Lennox-Gastaut syndrome

Interventions

Intervention 1: Orally levetiracetam with a dose of 250-500 milligram (mg) for 3 to 6 months. Intervention 2: Orally sodium valproate with a dose of 200-500 mg for 3 to 6 months.

Eligibility

Sex/Gender

All

Age

5 Years to 13 Years

Inclusion criteria

Inclusion criteria: Children aged 5-13 years old Children suffering generalized tonic-clonic seizures

Exclusion criteria

Exclusion criteria: Electrolyte imbalance in creatinine and urea nitrogen blood Sensitivity to drug

Design outcomes

Primary

Measure	Time frame
Recurrence of seizure. Timepoint: Every 6 months for one year. Method of measurement: Using EEG.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Reza Salehiomran

Babol University of Medical Sciences

salehiomran@yahoo.com+98 11 3234 2152

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026