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Checking the effect of oral Dydrogesterone (Duphaston) on preventing preterm labor

Checking the effect of oral Dydrogesterone (Duphaston) on preventing preterm labor: A Randomized Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190107042266N1
Enrollment
100
Registered
2019-03-04
Start date
2019-03-20
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm labor. Preterm labor

Interventions

Intervention 1: Intervention group: Dydrogesterone capsule with the dose of 10 milligrams, 2 tablets per day is prescribed after lunch and dinner and until the gestational age of 36 weeks and 6 days o

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: From the age of 18 to 45 Gestational age of 24 to 34 weeks (calculation based on first trimester sonography) Not having PLP 48 hours after treatment Single pregnancy Not of smoking

Exclusion criteria

Exclusion criteria: Placenta Previa Premature rupture of membranes Chorioamnionitis Severe preeclampsia The use of progesterone before the study Contraindication of progesterone Contraindication of Tocolytic Dilatation more than 4 centimeters Fetal anomalies Dissatisfaction of the patient to continue participating in the study Pregnancy scar Cervical cerclage

Design outcomes

Primary

MeasureTime frame
Preterm labor before the 37th week of pregnancy. Timepoint: From the beginning of the intervention (from the beginning of preterm labor up to the gestational age of 24 to 34 weeks) until the occurrence of the preterm labor (gestational age of 36 weeks and 6 days). Method of measurement: Visiting the patient every other two weeks for the relapse of preterm labor pain, regular use of drugs, drug based side effects like nausea, dizziness and exhaustion.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mojgan Rahmanian

Semnan University of Medical Sciences

sem.ums.res@gmail.com+98 23 3345 1336

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026