Post-treatment flare-up after using nano zinc oxide eugenol sealer

Post-treatment flare-up incidence after using nano zinc oxide eugenol sealer in mandibular first molars with irreversible pulpitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190103042224N1

Enrollment

Registered

2019-01-21

Start date

2018-10-02

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpitis : Irreversible. Diseases of pulp and periapical tissues

Interventions

Intervention 1: Intervention group: Application of nano zinc oxide eugenol sealer (produced by Dental Material Section of Mashhad Faculty of Dentistry) for root canal space obturation. Intervention 2:

Eligibility

Sex/Gender

All

Age

25 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients referred to Mashhad Faculty of Dentistry Patients suffering from acute dental pain due to irreversible pulpitis of first mandibular molars Absence of pulpal necrosis signs such as abscess, fistula or periapical radiolucency No history of taking analgesics during recent 8 hours

Exclusion criteria

Exclusion criteria: Lack of response to pulpal vitality tests Existence of periapical radiolucency Signs of acute periapical periodontitis Low to medium level dental pain History of significant medical condition

Design outcomes

Primary

Measure	Time frame
Evaluation of post-treatment pain severity. Timepoint: 6, 18, 24 and 48 hours post-treatment. Method of measurement: Visual Analog Scale.;Evaluation of post-treatment swelling existence. Timepoint: 6, 18, 24 and 48 hours post-treatment. Method of measurement: Questionnaire table (existence or absence of swelling).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Javidi Dasht Bayaz

Mashhad University of Medical Sciences

javidim@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026