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Effect of synbiotics in treatment of diarrhea

Evaluating the therapeutic effect of synbiotics on acute diarrhea in admitted children aged between 6-24 months; A randomized double blind placebo controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181231042190N1
Enrollment
120
Registered
2019-02-27
Start date
2019-03-10
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non infectious acute diarrhea. Noninfective neonatal diarrhea

Interventions

Intervention 1: Intervention group: Synbiotic drop orally at dose of 5 drops/day, one time daily for 5 days. Intervention 2: Control group: Placebo drop orally at dose of 5 drops/day, one time daily f

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Months to 24 Months

Inclusion criteria

Inclusion criteria: Children with diarrhea whose age is 24 to 6 months. Patients with acute non-bacterial diarrhea. The duration of diarrhea is less than two days. Patients with moderate dehydration. Patients with acute non-bloody diarrhea. Patients who use breast milk. Patients who have not taken antibiotics over the past two weeks. Patients whose parents have signed a consent form.

Exclusion criteria

Exclusion criteria: Patients with severe dehydration. Children who show no weight gain. Children who have taken antibiotics during diarrhea. Children who have severe vomiting. Children who have seizures. Patients found in their stool samples have inflammatory cells. Patients with a history of a variety of metabolic diseases. Children with a history of blood disorders and anemia. Patients with a history of a variety of digestive diseases. Patients who use formula milk. Patients with acute bloody diarrhea.

Design outcomes

Primary

MeasureTime frame
Time of Hospitalization. Timepoint: The duration of treatment. Method of measurement: The duration of hospitalization.

Secondary

MeasureTime frame
Pharmaceutical allergy. Timepoint: The duration of treatment. Method of measurement: Clinical observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Azadeh Arefian

Ahvaz University of Medical Sciences

azadeh.aref@yahoo.com+98 61 3444 9003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026