Comparison of intravenous remifentanil and intravenous lidocaine in prevention of cardiovascular response to laryngeal mask airway insertionl following anesthesia in limbs surgery.

Comparison of remifentanil and lidocaine on controlling the cardiovascular response to laryngeal mask airway insertion following general anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181229042169N1

Enrollment

Registered

2020-12-07

Start date

2020-08-22

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open reduction and internal fixation of ulna and radiusfracture. Fracture of shaft of radius

Interventions

Intervention 1: Intervention group: participants in intervention group after induction of anesthesia receives intravenous Remifentanil with a dose of 1.5 microgram/kg, and after 2 minutes ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Male or female 18 - 60 years old Open limbs surgery under general anesthesia Class 1 and 2 of anesthesia risk (According to American society of anesthesiologist's classification)

Exclusion criteria

Exclusion criteria: Difficult LMA placements Repeated attempts at LMA insertion Prolonged ( more than 30 seconds) LMA insertion

Design outcomes

Primary

Measure	Time frame
Systolic Blood pressure. Timepoint: Before induction of anesthesia - after induction of anesthesia - and immediately after laryngeal mask airway insertion. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.;Diastolic blood pressure. Timepoint: Before induction of anesthesia - after induction of anesthesia - and immediately after laryngeal mask airway insertion. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.;Pulse rate. Timepoint: Before induction of anesthesia - after induction of anesthesia - and immediately after laryngeal mask airway insertion. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.	—

Measure

Time frame

Systolic Blood pressure. Timepoint: Before induction of anesthesia - after induction of anesthesia - and immediately after laryngeal mask airway insertion. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.;Diastolic blood pressure. Timepoint: Before induction of anesthesia - after induction of anesthesia - and immediately after laryngeal mask airway insertion. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.;Pulse rate. Timepoint: Before induction of anesthesia - after induction of anesthesia - and immediately after laryngeal mask airway insertion. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Javad Nourian

Shahroud University of Medical Sciences

javadnourian@gmail.com+98 23 3239 5054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026