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Evaluation of the effect of mesotherapy in the treatment of hair loss

Evaluation of the effect of mesotherapy with a combination of biotin and dexpanthenol in the treatment of androgenetic alopecia in women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181226042136N2
Enrollment
36
Registered
2020-08-31
Start date
2020-04-19
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female androgenetic alopecia. Androgenic alopecia

Interventions

Intervention 1: Intervention group: In the case group, patients undergoing mesotherapy with microneedling with a solution of 20 mg of biotin + 500 mg of dexpanthenol per month plus topical minoxidil 2

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Having a female pattern hair loss Do not use other hair loss treatments at the time of enrollment Do not use temporary and permanent hair dye and curl or straighten hair Do not use aspirin, warfarin, steroids, oral retinoids, hormones or cytotoxic drugs Absence of pregnancy and lactation Absence of high androgenic blood levels, irregular periods, acne and hirsutism, thromboembolic events, low ferritin blood levels and impaired TSH

Exclusion criteria

Exclusion criteria: Allergic reaction to the drug used Failure to complete the course of treatment and failure to refer for follow-up, which results in a drawing on the case file or the patient Local reactions such as abscesses, inflammation and cellulite at the injection site The patient's decision not to participate in the study

Design outcomes

Primary

MeasureTime frame
Appearance based on photography. Timepoint: Photographs will be taken first before the start of treatment and finally two weeks after the microneedling sessions. Method of measurement: By a dermatologist.;Intensity based on Ludwig Griding. Timepoint: It is performed before treatment and at 18 weeks by a dermatologist who is unaware of the patient's grouping. Method of measurement: By a dermatologist.;Number of hairs plucked in the hair pulling test. Timepoint: The number of hairs removed before treatment and after 18 weeks is counted and recorded. Method of measurement: In the hair pull test, about 20-30 hairs in the vortex area between the thumb and the other 4 fingers are gently pulled and pulled vertically.;Patient opinion about density, thickness, hair loss and quality. Timepoint: before and after the treatment. Method of measurement: In the self-assessment of the patient, the result of the treatment is asked about increasing hair density, increasing hair thickness, hair loss rate and hair quality (color and transparency). Answers are considered as worsening 1-, without changing 0 and improving 1.

Secondary

MeasureTime frame
Complications. Timepoint: In each session. Method of measurement: Complications of treatment in each session, including headache, cramping, itching, ecchymosis, puffy eyes, increased hair growth in other parts of the body and changes in menstrual patterns, patients are asked and recorded.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZakiye Ganjei

Esfahan University of Medical Sciences

z.ganjei@gmail.com+98 31 3668 7270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026