Tranexamic acid in brain contusion clinical trial

Evaluating the effect of tranexamic acid on prevention of brain contusion, a clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181225042112N1

Enrollment

Registered

2019-02-14

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic brain injury. Focal traumatic brain injury

Interventions

Intervention 1: Intervention group: administration of tranexamic acid. Intervention 2: Control group: administration of normal saline.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: non-surgical patients with moderate to severe head trauma (GCS: 3-12) with brain contusion

Exclusion criteria

Exclusion criteria: active bleeding in other sites other causes that necessitates use of tranexamic acid renal failure and creatinine more than 2

Design outcomes

Primary

Measure	Time frame
Contusion evolution. Timepoint: every day in a week. Method of measurement: measuring the CT scan cuts.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Jahanbakhshi

Iran University of Medical Sciences

jahanbakhshi.a@iums.ac.ir+98 21 86701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026