Preserving fertility following chemotherapy.
Conditions
Interventions
Intervention 1: Intervention group: The GNRH intervention group is prescribed at least 2 weeks before starting treatment and every 28 days during treatment with a chemotherapy regimen. Intervention 2:
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
13 Years to 50 Years
Inclusion criteria
Inclusion criteria: Women with cancer who require chemotherapy Age of more than 13 and less than 50 years old Good performance (ECOG: 0-1 No history of previous chemotherapy Sign a Consent Form Dissatisfaction with oocyte fusion
Exclusion criteria
Exclusion criteria: Pregnancy / Breastfeeding2. 3. 4. 6. Hypersensitivity reaction or significant side effect of the drug History of thromboembolic events in the patient The history of osteoporotic fractures Patient does not cooperate in the correct treatment process in accordance with the recommended guidelines
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination of the effect of GNRH on preservation of fertility and ovarian function in patients undergoing combined chemotherapy. Timepoint: Check immediately and 6 months after chemotherapy. Method of measurement: Perform ovary function assessment tests.;Menstural recovery. Timepoint: 6 months after treatment. Method of measurement: Question from the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Mozaheb
Mashhad University of Medical Sciences
Outcome results
None listed