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Investigating the effect of keratinocyte cells in healing deep burns

Investigating the regenerative effect of non-cultivable autologous keratinocyte cells in deep burns receiving skin.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181222042074N3
Enrollment
106
Registered
2022-09-28
Start date
2022-09-21
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

deep burn. Burn of second degree of trunk

Interventions

Intervention 1: Intervention group: In addition to receiving skin with a one-to-three mesh like the control group, they will also receive keratinocyte cells extracted from a remnant of their own skin

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 55 years Thermal burns of 20-50%, at least 15% of which are deep 2nd degree or 3rd degree ??????? ????? ??????? ???? ? ???? ????? ???? ???? ?????? ?? ?????? Written consent to participate in the research project

Exclusion criteria

Exclusion criteria: Inhalation damage Chemical or electrical burns Treatment of reducing the patient's level of consciousness during hospitalization pregnant mothers

Design outcomes

Primary

MeasureTime frame
Investigating the function of keratinocyte cells in deep burns. Timepoint: weekly. Method of measurement: Clinical examinations.;Wound healing rate. Timepoint: weekly. Method of measurement: Clinical examinations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ahmad Abadi

Mashhad University of Medical Sciences

ahmadabadia@muma.ac.ir+98 51 3854 3031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026