Evaluation of the effect of amniotic scaffold and keratinocyte cells on wound healing from butterfly wing disease

Design and evaluation of biological dressing efficiency with tissue engineering structure in wound healing of Epidermolysis bullosa patients: the first stage of phase 2

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181222042074N2

Enrollment

Registered

2022-06-29

Start date

2022-07-21

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidermolysis bullosa. Epidermolysis bullosa

Interventions

Intervention 1: Intervention group 1: Amniotic scaffold with adipose stem cells. Isolated samples are used for liposuction to extract MSCs. Tissue tissue is treated with type 2 collagenase enzyme and

Eligibility

Sex/Gender

All

Age

No minimum to 10 Years

Inclusion criteria

Inclusion criteria: People with a diagnosis of butterfly wing genetic disease Agreeing with informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Reluctance to cooperate Complications in wounds such as infections

Design outcomes

Primary

Measure	Time frame
Wound healing rate. Timepoint: weekly. Method of measurement: Clinical examinations.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShirin Toosi

Mashhad University of Medical Sciences

Toosis@mums.ac.ir0517034785

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026