Comparison of Continuous Moderate-Intensity Training and High-Intensity Interval Training on Vasodilators And Cardiac Function in Type 2 Diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181219042056N1

Enrollment

Registered

2019-05-13

Start date

2017-11-01

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Type 2 diabetes mellitus

Interventions

Intervention 1: Intervention group 1: Doing 12 weeks continuous moderate-intensity training (70 % Heart Rate max) on cycle , every week 3 times and every time 1 hour pedal. Intervention 2: Interventio

Eligibility

Sex/Gender

All

Age

45 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 45 to 60 years. According to Defined by American Diabetes Association 2015, fasting blood sugar (FBS) more than 7 mmol/L. Glycosylated Haemoglobin (HbA1c) above 6%. Type 2 Diabetes. Pre- or stage I hypertension, or treated hypertension (systolic blood pressure 120–159 mmHg, diastolic blood pressure 80–99 mmHg). Patients with history of Type 2 Diabetes for at least 2 years. No exercise training in the previous 6 months.

Exclusion criteria

Exclusion criteria: Patients with FBS more than 22 mmol/L. HbA1c above 10%. Myocardial infarction, coronary artery bypass surgery or angioplasty, chronic heart failure, cardiac arrhythmia, functional limitations (such as osteoarthritis), liver or kidney disease, and smoking. Hypertension, or treated hypertension (systolic blood pressure 170 mmHg, diastolic blood pressure 100 mmHg).

Design outcomes

Primary

Measure	Time frame
Adropin Factor. Timepoint: Before and After from 12 week exercise. Method of measurement: Using the Laboratory Elisa Kit.;Nitrite/Nitrate plasma. Timepoint: Before and After from 12 week exercise. Method of measurement: Using the Laboratory Elisa Kit.;HOMA-IR. Timepoint: Before and After from 12 week exercise. Method of measurement: HOMA-IR.;Glucose. Timepoint: Before and After from 12 week exercise. Method of measurement: Enzymatic.;Peak consumption oxygen. Timepoint: Before and After from 12 week exercise. Method of measurement: Gas analyser system.;Diastolic and systolic blood pressure. Timepoint: Before and After from 12 week exercise. Method of measurement: oscillometric device.;Heart rate rest. Timepoint: Before and After from 12 week exercise. Method of measurement: Cornometer/ numbere.;Insulin. Timepoint: Before and After from 12 week exercise. Method of measurement: ELISA kit.	—

Measure

Time frame

Adropin Factor. Timepoint: Before and After from 12 week exercise. Method of measurement: Using the Laboratory Elisa Kit.;Nitrite/Nitrate plasma. Timepoint: Before and After from 12 week exercise. Method of measurement: Using the Laboratory Elisa Kit.;HOMA-IR. Timepoint: Before and After from 12 week exercise. Method of measurement: HOMA-IR.;Glucose. Timepoint: Before and After from 12 week exercise. Method of measurement: Enzymatic.;Peak consumption oxygen. Timepoint: Before and After from 12 week exercise. Method of measurement: Gas analyser system.;Diastolic and systolic blood pressure. Timepoint: Before and After from 12 week exercise. Method of measurement: oscillometric device.;Heart rate rest. Timepoint: Before and After from 12 week exercise. Method of measurement: Cornometer/ numbere.;Insulin. Timepoint: Before and After from 12 week exercise. Method of measurement: ELISA kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Salehi

Vice president of of Research of Tehran University

salehi.1371@ut.ac.ir+98 21 8835 1730

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026