Skip to content

Assessment of jadwar capsule on clinical manifestation of knee Osteoarthritis

Assessment of the effect of jadwar capsule (delphinium denudatum) on clinical manifestation of knee Osteoartheritis versus Placebo : A double blind randomized controlled clinical trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181218042037N1
Enrollment
94
Registered
2019-06-13
Start date
2019-06-15
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: In this group participants receive 500 m/g of jadwar capsul in the morning and at night for 4 weeks. jadwar Capsules are Produced in the shafanegar nazary pharmac

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Mild to moderate knee Ostoarthritis patients according to Kellegren-Lawrence (K-L) grading scale Pain at least in one knee in last 3 month ago Minimum annoying pain (at least 4 ) before randomized selection according to VAS scale

Exclusion criteria

Exclusion criteria: Allergy to oral consumption of jadwar capsul. Secondary Osteoarthritis as Rhuomatoid arthritis,Gout,Infectious arthritis,Metabolic arthritis,Traumatic arthritis. Operative knee joint replacement . Topical or systemic steroid use since 14 day before study . Intraarticular steroid injection since 90 day before study . Pregnancy and lactation period . Alcohol and opioid addiction Radiculopathy and Neuropathy . History of any kind of knee operation and trauma Utilization of other analgesic drugs since study period History of renal failure or heart failure or hepatic failure

Design outcomes

Primary

MeasureTime frame
Score of knee pain intensity. Timepoint: Measuring the Score of knee pain intensity at the beginning of the study and 14 and 28 days after starting use of jadwar capsul. Method of measurement: Visual Analogue Scale.;Daily activity Score. Timepoint: Measuring of Daily activity Score at the beginning of the study and 14 and 28 days after starting use of jadwar capsul. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRogayeh Baghervandnavid

Tabriz University of Medical Sciences

baghervandnavid@tbzmwd.ac.ir+98 41 3382 6501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026