Betadine versus metronidazole gel for post-cesarean section infections

Vaginal preparation with povidone-iodine versus metronidazole for preventing post-Cesarean infections

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181218042033N5

Enrollment

426

Registered

2022-07-15

Start date

2021-11-22

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-cesarean section infection. Endometritis following delivery

Interventions

Intervention 1: Control group: Abdominal skin preparation using 7.5% povidone-iodine (Iran Najo Co., Tehran, Iran) and then draping using sterile surgical drapes before cesarean section. Intervention

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Elective cesarean section Singleton pregnancy

Exclusion criteria

Exclusion criteria: Severe bleeding Hypersensitivity to metronidazole or povidone-iodine Active genital herpes Severe anemia (hematocrit 30 kg/m2 Preeclampsia Diabetes mellitus Antibiotic or corticosteroid use Rupture of membranes Chorioamnionitis Fever due to any cause prior to cesarean section (temperature >38 C)

Design outcomes

Primary

Measure	Time frame
Endometritis. Timepoint: Up to 15 days after cesarean section. Method of measurement: Clinical examination.	—

Secondary

Measure	Time frame
Wound infection. Timepoint: Up to 15 days after cesarean section. Method of measurement: Clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Abdi

Bandare-abbas University of Medical Sciences

abdinazanain834@gmail.com+98 76 3333 5934

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026