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Comparison of the efficacy of domestic allergenic extracts with matched commercial imported extracts

A multi-centers Non-inferiority clinical trials for evaluating the efficacy of inhalant and food allergic extracts made from domestic sources by skin prick testing in comparison of their matched commercial extracts on a group of patients with history of allergic diseases visiting allergy clinics

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181216042006N1
Enrollment
107
Registered
2020-12-07
Start date
2020-12-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Allergic rhinitis. Condition 2: Asthma. Condition 3: Atopic dermatitis. Condition 4: Food allergy. Allergic rhinitis due to pollen Asthma Atopic dermatitis Food allergy status

Interventions

Intervention 1: Intervention group: allergic patients who are referred to allergy clinic and are candidate of skin prick test with commercial extracts from Stallergen or Greer Companies. Based on the

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 60 Years

Inclusion criteria

Inclusion criteria: patients with history of allergy to inhalant or food allergens who visit allergy clinics and are candidate of performing skin prick test by specialist

Exclusion criteria

Exclusion criteria: Having serious health problems such as cancer, immunodeficiency, autoimmunity, cardiac disease and severe infection Pregnancy or breastfeeding History of anaphylaxis or uncontrolled asthma Current dermatographism or urticaria History of allergy immunotherapy during the last 5 years Using medicine which interfere with skin prick test such as antihistamines, oral corticosteroids, narcotics or sedatives during the last week

Design outcomes

Primary

MeasureTime frame
Positive skin reactivity to domestic extracts in comparison to commercial extracts. Timepoint: 15 minutes after doing skin prick test. Method of measurement: Area of wheal created by extracts in square milometers.

Secondary

MeasureTime frame
Side effects of skin prick testing with commercial or domestic extracts including large local reactions or systemic reactions. Timepoint: during the first 24 hours after doing skin prick test. Method of measurement: A design questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Fereidouni

Birjand University of Medical Sciences

dr.m.fereidouni@gmail.com009856323381500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026