Comparison of dressing with Amniotic membrane and Nitrofurazone ointment in second degree burn wound

Comparison of dressing with Amniotic membrane and Nitrofurazone ointment in second degree burn wound in THE IMAM KHOMEYNI hospital of URMIA

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181216041996N1

Enrollment

Registered

2019-01-22

Start date

2019-01-21

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial second-degree burns. Calcification and ossification of muscles associated with burns, unspecified site

Interventions

Intervention 1: Intervention group: the amniotic membrane donated by the hospital was used to dress the superficial second-degree wound. Intervention 2: Control group: In the dressing group with nitro

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: superficial second-degree burn in all age groups

Exclusion criteria

Exclusion criteria: unstable vital signs, history of psychiatric disorders in patients with burns smoking, drug and psychotropic substance addiction history of heart, kidney, and liver diseases, diabetes, malnutrition, history of corticosteroids or immunosuppressive drugs use, inhalation and old burns evidence of infection in burns reaction and hypersensitivity to nitrofurazone ointment as well as to dressing with amniotic membrane need for wound debridement in operation room non-referral of patients after hospital discharge

Design outcomes

Primary

Measure	Time frame
Wound infection. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: observation . examination.;, severity of pain in the dressing site. Timepoint: first 7 days. Method of measurement: The severity of pain was measured using Visual Analogue Scale 0 to 10 numeric pain distress scale- on which the patient left marks based on their pain sensation.;Level of epithelialization. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: observation.;Hospitalization period. Timepoint: hospitalization period. Method of measurement: observation.;Frequency of dressing changes. Timepoint: first 7 days. Method of measurement: observation.;Analgesic use. Timepoint: first 7 days. Method of measurement: observation.;Wound scarring rate. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: Vancouver scar score.	—

Measure

Time frame

Wound infection. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: observation . examination.;, severity of pain in the dressing site. Timepoint: first 7 days. Method of measurement: The severity of pain was measured using Visual Analogue Scale 0 to 10 numeric pain distress scale- on which the patient left marks based on their pain sensation.;Level of epithelialization. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: observation.;Hospitalization period. Timepoint: hospitalization period. Method of measurement: observation.;Frequency of dressing changes. Timepoint: first 7 days. Method of measurement: observation.;Analgesic use. Timepoint: first 7 days. Method of measurement: observation.;Wound scarring rate. Timepoint: seventh, fourteenth, and thirtieth days. Method of measurement: Vancouver scar score.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Zahedi

Oroumia University of Medical Sciences

dr.afshinz@yahoo.com+98 44 3346 9931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 12, 2026