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Evaluation the safety efficacy bilaterally dosed topical lipoic acid cyclodexterin eye drops for the treatment presbyopia.

Evaluation the safety efficacy bilaterally dosed topical lipoic acid cyclodexterin eye drops for the treatment presbyopia.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181215041972N1
Enrollment
30
Registered
2019-03-14
Start date
2018-12-11
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Presbyopia. Accommodation and refraction

Interventions

Intervention 1: Intervention group: 15 patients with close visual impairment of drops of lipoic acid + cyclodextrin drops are treated for 90 days and twice a day. Intervention 2: Control group: 15 pa

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 55 Years

Inclusion criteria

Inclusion criteria: BCDVA of 20/20 DCNVA worsen than 20/40 in each eye Age 40-55 years old

Exclusion criteria

Exclusion criteria: Without any underlying disease

Design outcomes

Primary

MeasureTime frame
Evaluation of efficacy and side effect of lipoic acid eye drops in presbyopic with sample 30 patienat Due to the effect of the medication on the near vision. Timepoint: Day one, Day 15, Day 30, Day 60, Day 90. Method of measurement: Measurement of refractive error of the eye in close and distant vision.;Amplitude of accommodation. Timepoint: Day one, Day 15, Day 30, Day 60, Day 90. Method of measurement: Based on the NPA method and lens.;Evaluation of side effects Like asthenopia, conjunctival hyperemia, blurred vision. Timepoint: Day one, Day 15, Day 30, Day 60, Day 90. Method of measurement: Based on Clinical Examination with Slit Lamp and Clinical history.

Secondary

MeasureTime frame
The presence or absence of side effects of the medication on the patient's eyes. Timepoint: The first day after 2 weeks - again after 2 weeks - the next month - the next month. Method of measurement: By complete ophthalmic examinations with a slide machine by an ophthalmologist from the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Gharaee

Mashhad University of Medical Sciences

gharaeeh@mums.ac.ir+98 517289911

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026