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The effect of grape seed extract vaginal cream on the treatment of candidal vaginitis

Comparison of the effect of vaginal cream of grape seed extract and clotrimazole on the treatment of candida vaginitis: a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181214041963N3
Enrollment
70
Registered
2023-03-08
Start date
2023-04-04
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candida vaginitis. Candidiasis of vulva and vagina

Interventions

Intervention 1: Intervention group: grape seed cream, which will be made in Jundishapur Faculty of Pharmacy of Medical Sciences. To prepare medicine, 35 empty metal tubes of 50 grams with 2% grape se

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Consent to participate in research Diagnosis of candidal vaginitis (at least 3 points out of 18 symptom points), Marriage history Not being pregnant Lack of breastfeeding Not suffering from diabetes mellitus and diseases that weaken the immune system Not using broad-spectrum antibiotics in the last 2 weeks Not using vaginal douche in the last 48 hours Not using vaginal drugs during the last week Not using hormonal drugs during the last 3 months Not having audio Not having a candidal infection more than 4 times a year

Exclusion criteria

Exclusion criteria: Vaginal bleeding Addiction and alcohol consumption Allergy to grapes

Design outcomes

Primary

MeasureTime frame
Improvement of candidiasis signs. Timepoint: 6-8 next days. Method of measurement: Examination and laboratory test and check list.

Secondary

MeasureTime frame
Improvement of disease recurrence. Timepoint: 40 days after the intervention. Method of measurement: Examination and laboratory test and checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Ebrahimian

Ahvaz University of Medical Sciences

ebrahimiyan127@gmail.com+98 61 3311 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026