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Comparison of the Effectiveness of Hydrochlorothiazide with Nasal Spray of Desmopressin in Treatment of Nocturia in Children Referring to Pediatric Nephrology Clinic in hamadan in first 6 month of 2019

Comparison of the Effectiveness of Hydrochlorothiazide with Nasal Spray of Desmopressin in Treatment of Nocturia in Children Referring to Pediatric Nephrology Clinic in hamadan in first 6 month of 2019

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181212041936N1
Enrollment
208
Registered
2019-01-23
Start date
2018-09-22
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enuresis. Nonorganic enuresis

Interventions

Intervention 1: Intervention group: hydrochlorothiazide. Intervention 2: Control group: nasal spray desmopressin.

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 18 Years

Inclusion criteria

Inclusion criteria: All girls aged more than 5 years old and all boys over 6 years of age with diagnosis of primary monosymptomatic nocturnal enuresis referred to the nephrology clinic of children

Exclusion criteria

Exclusion criteria: Anatomical disorders lead to urinary incontinence such as neurogenic bladder, posterior ureteral valve and anatomical disorders of the ureter Metabolic disorders leading to polyuria such as diabetes mellitus and diabetes insipid secondary nocturnal enuresis polysymptomatic nocturnal enuresis Parental dissatisfaction adverse effects of drugs

Design outcomes

Primary

MeasureTime frame
Resolved of Enuresis. Timepoint: Patients are followed up for a period of 6 months, and the outcome of the disease is the drying up of the child during sleep during medication three months and within three months after it, after discontinuation of drugs, in addition to monthly monitoring during the monthly visits to the families It will be explained if the child reports wetting the next day and if the child remains dry. Meanwhile, after the discontinuation of the medications within the next three months, follow-up and drying or returning of the enuresis will be considered. Method of measurement: Completion of follow-up questionnaires.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFahimeh Ahmadvand

Hamedan University of Medical Sciences

Fahimeeee2@gmail.com+98 81 3264 0022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026