Condition 1: Type 2 diabetes. Condition 2: Obesity. Diabetes mellitus due to underlying condition Overweight and obesity
Conditions
Interventions
Intervention 1: Intervention group: They will receive energy balanced diet + 30 g/day dry ziziphus jujube once a day for 10 weeks. Energy balanced diet will be considered for Individuals based on food
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: Agreement to participate in the study and completing informed consent form Aged 35-65 years old The duration of the disease should be between 1 to 10 years Fasting blood glucose and 2-h blood glucose should be less than 126 and 200 mg / dl, respectively. Body mass index=25 kg/m2 Patients who take only oral medication (not insulin) to control diabetes.
Exclusion criteria
Exclusion criteria: having allergy to dry jujube using of alcohol, opioids, and anti-inflammatory drugs. using of multi-vitamin mineral supplements, administration of clozapine, theophylline, caffeine, fennetin and tacrin. Pregnant and lactating Women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum concentrations of blood glucose. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: Enzymatic method.;Serum concentrations of total cholesterol. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: Enzymatic method.;Serum concentrations of triglyceride. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: Enzymatic method.;Low density lipoprotein- cholesterol. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: Enzymatic method.;High density lipoprotein- cholesterol. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: Enzymatic method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum concentration of Insulin. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: ELISA method.;Serum concentration of malondialdehyde. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: Colorimetric method.;Serum concentration of Carboxy-methyl lysine. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: ELISA method.;Serum concentration of Interleukin-6. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: ELISA method.;Serum concentration of hs-CRP. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: ELISA method.;Serum concentration of fructoseamine. Timepoint: Before the intervention and 10 weeks after the intervention. Method of measurement: ELISA method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Farhadnejad
Shahid Beheshti University of Medical Sciences
Outcome results
None listed