Vascular Dementia. occlusion and stenosis of cerebral and precerebral arteries (including truncus brachiocephalicus), resulting in cerebral infarction
Conditions
Interventions
Intervention 1: Intervention group: Donpezil starts at 5mg / day and increases to 10mg / day within two weeks and lasts up to three months. Intervention 2: Intervention group: Rivastigmine starts at
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with vascular dementia in Kerman city
Exclusion criteria
Exclusion criteria: Having any underlying condition other than diabetes, hypertension, hyperlipidemia, and ischemic heart disease, including history of depression and memory and speech impairment. Use of any medication, such as sedative medicines and substance abuse, except medicines for controlling diabetes, hypertension, hyperlipidemia, and ischemic heart disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transcranial Doppler Sonography. Timepoint: Performing transcranial doppler sonography at the beginning of the study and three months after taking any of the donepezill, memantine, galanthamine or rivastigmine drugs. Method of measurement: Doppler Sonography machine. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini Mental State Examination. Timepoint: Measurement of the MMSE at the beginning of the study and three months after the onset of consumption, which of the drugs donepezil, memantine, galantamine or rivastigmine. Method of measurement: By number from zero to thirty. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhad Iranmanesh
Kerman University of Medical Sciences
Outcome results
None listed