The Effect of Nigella Sativa Oil on Phlebitis

Evaluation of the Effect of Nigella Sativa Oil in the Prevention of Chemotherapy- Induced Phlebitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181208041892N1

Enrollment

Registered

2018-12-26

Start date

2018-10-04

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Phlebitis. Vascular complications following infusion, transfusion and therapeutic injection

Interventions

Intervention 1: Intervention group: 5 drops of Nigella Sativa oil (prepared by the pharmacist) was rubbed around the area of intravenous chemotherapy injection, every 12 hours (morning and night befor

Eligibility

Sex/Gender

All

Age

25 Years to 75 Years

Inclusion criteria

Inclusion criteria: Consciousness & Patient cooperation Age between 25-75 years Admitted to hospital with Gastrointestinal cancer (colon, rectum, esophagus, stomach) Chemotherapeutic management with 5-fluorouracil & Oxaloplatin & Leukovein or 5-fluorouracil & Cisplatin Catheterization into arm vein Application No. 20-22 catheter Unicut Company Instructions no received antibiotic & Non-steroidal anti-inflammatory drugs Without diabetes, Skin disorders and Autoimmune diseases Stable hemodynamic status Not addiction Hospitalized in the Oncology Ward of Tohid Hospital Without fever & neutropenia

Exclusion criteria

Exclusion criteria: Unwillingness to be in the study Worsen the condition of patient during the study Incidence of allergic reactions during the study Acute infection

Design outcomes

Primary

Measure	Time frame
Phlebitis. Timepoint: Every 12 hours over 72 hours after intervention. Method of measurement: observation, Visual Infusion Phlebitis Scale ( VIP).	—

Secondary

Measure	Time frame
Pain, Erythema and Swelling. Timepoint: Every 12 hours over 72 hours. Method of measurement: Observation, Visual infusion phlebitis Scale (VIP).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiaz Behnamfar

Islamic Azad University

Niaaz.Behnamfar@gmail.com+98 21 2200 6660

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026