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The effect of Montelukast on COVID 19 disease activity

Evaluation of the effect of Montelukast drug in improving the clinical condition of patients with COVID-19 in referral hospitals in Isfahan

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181208041886N3
Enrollment
60
Registered
2020-12-22
Start date
2020-12-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID-19, virus identified

Interventions

Intervention 1: Intervention group: the patients with diagnosis of COVID-19 will be treated by tablet Montelukast 10 mg. This treatment will be in addition to standard therapies for these patients. Th

Sponsors

Abidi Pharmaceutical company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Every patient with diagnosis of COVID-19 Mild, moderate and severe stage of the disease

Exclusion criteria

Exclusion criteria: No complete consent and compliace of the patient for study Follow up of the patient not be possible The age below 15 years old Rifampin and Phenobarbital consumers

Design outcomes

Primary

MeasureTime frame
Discontinuation of fever. Timepoint: Daily till 14 days. Method of measurement: Measurement of temperature by digital infrared thermometer, and the O2 saturation by pulseoximeter.;Decreased Respiratory Rate. Timepoint: Daily till 14 days. Method of measurement: Measurement of fever by a termometer, and O2 saturation by pulse Oximetery.;Decreased Cough. Timepoint: Daily till 14 days. Method of measurement: Body temperature by thermometer, O2 sat by pulseoximetery.;Evaluation of blood O2 Saturation. Timepoint: Daily till 14 days. Method of measurement: Physician evaluation by Puls oxymetery.

Secondary

MeasureTime frame
Improvement of the patient with diagnosis of COVID-19 infection. Timepoint: Daily till 14 days. Method of measurement: Evaluation by Physician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Pourahmad

Esfahan University of Medical Sciences

mortezapourahmad@yahoo.com+98 31 3322 0996

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026