Evaluation of curcumin gel effevtiveness in prophylaxis of radiation dermatitis

Evaluation of 2% curcumin gel effevtiveness in prophylaxis of radiation dermatitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181208041882N3

Enrollment

Registered

2020-11-06

Start date

2019-06-16

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dermatitis caused by breast radiation therapy. Radiodermatitis

Interventions

Intervention 1: Intervention group: Curcumin gel 2% twice daily from the first day Radiation therapy The patient receives one of the same gels topically for four weeks. Made in Yazd University

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Women 18 to 65 years old to get started breast radiation therapy has been referred to Shahid Ramezanzadeh Radiotherapy Center in Yazd

Exclusion criteria

Exclusion criteria: People with skin diseases People who are allergic to curcumin People with severe systemic diseases such as uncontrolled diabetes

Design outcomes

Primary

Measure	Time frame
Intensity of redness. Timepoint: The severity of the redness begins with treatment Redness intensity in the first week Redness intensity in the second week Redness intensity in the third week and redness intensity in the fourth week after starting treatment. Method of measurement: RTOG standard scale.;Itching intensity. Timepoint: The severity of itching begins treatment Severity of itching in the first week Severity of itching in the second week Severity of itching in the third week and severity of itching in the fourth week after starting treatment. Method of measurement: Based on a question from the patient.;Intensity of burning. Timepoint: Severe onset of burning of treatment of severity of burning in the first week, severity of burning in the second week, severity of burning in the third week, and severity of burning in the fourth week after starting treatment. Method of measurement: Based on a question from the patient.;Intensity of pain. Timepoint: Intensity of pain Initiation of treatment Intensity of pain The first week Pain intensity in the second week Pain intensity in the third week and pain intensity in the fourth week after starting treatment. Method of measurement: Based on a question from the patient.	—

Measure

Time frame

Intensity of redness. Timepoint: The severity of the redness begins with treatment Redness intensity in the first week Redness intensity in the second week Redness intensity in the third week and redness intensity in the fourth week after starting treatment. Method of measurement: RTOG standard scale.;Itching intensity. Timepoint: The severity of itching begins treatment Severity of itching in the first week Severity of itching in the second week Severity of itching in the third week and severity of itching in the fourth week after starting treatment. Method of measurement: Based on a question from the patient.;Intensity of burning. Timepoint: Severe onset of burning of treatment of severity of burning in the first week, severity of burning in the second week, severity of burning in the third week, and severity of burning in the fourth week after starting treatment. Method of measurement: Based on a question from the patient.;Intensity of pain. Timepoint: Intensity of pain Initiation of treatment Intensity of pain The first week Pain intensity in the second week Pain intensity in the third week and pain intensity in the fourth week after starting treatment. Method of measurement: Based on a question from the patient.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehrooz Heydari

Yazd University of Medical Sciences

b.heydari@ssu.ac.ir+98 35 3820 3410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026