Effect of dexamethasone injection on reducing complications due to impacted wisdom tooth surgery

Comparison of efficacy of pre-operative dexamethasone injection into masseter muscle versus gluteus major muscle on reducing complications due to impacted mandibular third molar surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181204041849N1

Enrollment

Registered

2019-02-10

Start date

2019-01-01

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impacted mandibular third molar surgery.

Interventions

Intervention 1: Intervention group: injection of Dexamethasone 8 mg into the Masseter muscle 1-2 hours before surgery & after inferior alveolar nerve block injection for one side surgery. Intervention

Eligibility

Sex/Gender

All

Age

15 Years to 35 Years

Inclusion criteria

Inclusion criteria: People who have impacted mandibular wisdom tooth in both sides with same difficulty. People who don`t have pericoronitis & infection.

Exclusion criteria

Exclusion criteria: Pregnant women People who have uncontrolled systemic disease. People who have sensitivity to the drugs that are being used in the study. Use of drugs that interfere with dexamethasone.

Design outcomes

Primary

Measure	Time frame
Edema. Timepoint: Before the surgery, second & seventh day after surgery. Method of measurement: Swelling will be measured by a flexible ruler & the distance between the facial landmarks (tragus-pogonium, tragus-commissur of the lip, angle of mandible-outer canthus of eye) in millimeters.;Pain. Timepoint: Surgical day, Day 1, Day 3 and Seventh day after surgery. Method of measurement: Patients score 10-0 according to the Standard Visual Analog Scale.;Trismus. Timepoint: Before the surgery, second & seventh day after surgery. Method of measurement: Measure the distance between the edges of the upper and lower central incisors by a graded ruler, when the patient opens the mouth to the extent possible.	—

Measure

Time frame

Edema. Timepoint: Before the surgery, second & seventh day after surgery. Method of measurement: Swelling will be measured by a flexible ruler & the distance between the facial landmarks (tragus-pogonium, tragus-commissur of the lip, angle of mandible-outer canthus of eye) in millimeters.;Pain. Timepoint: Surgical day, Day 1, Day 3 and Seventh day after surgery. Method of measurement: Patients score 10-0 according to the Standard Visual Analog Scale.;Trismus. Timepoint: Before the surgery, second & seventh day after surgery. Method of measurement: Measure the distance between the edges of the upper and lower central incisors by a graded ruler, when the patient opens the mouth to the extent possible.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepideh Etemadzadeh

Bojnourd University of Medical Sciences

s.etemadzade@gmail.com+98 58 3624 5629

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026