The effect of snacks fortified with vitamin D, iron, zinc and L-arginine on malnutrition

Evaluating the effect of snack fortified with vitamin D, iron, zinc and arginine compared with conventional snack on the anthropometric indices of malnourished children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181204041843N1

Enrollment

120

Registered

2019-01-25

Start date

2018-09-21

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition. Protein-calorie malnutrition of moderate and mild degree

Interventions

Intervention 1: Intervention group: Daily intake of 200 ml of dairy snack fortified with 5 g of arginine, 4 g of zinc, 4 g of iron and 500 units of vitamin D for 90 days. Intervention 2: Control group

Eligibility

Sex/Gender

Male

Age

6 Years to 10 Years

Inclusion criteria

Inclusion criteria: Aged between 6 and 10 years Children with a weight for age chart below the 5th percentile Children whose parents have completed the informed consent form

Exclusion criteria

Exclusion criteria: Serious medical illnesses including neurologic, cancer, thyroid, cardiovascular, gastrointestinal, endocrine, renal, hepatic and eating disorders Children with long-term short stature Intake of medications that could affect body weight, appetite, vitamin D, zinc and iron metabolism Participation in any other weight management studies within the last 6 months Taking multivitamin-mineral supplements and other food supplements

Design outcomes

Primary

Measure	Time frame
Weight for age. Timepoint: Before intervention, after intervention. Method of measurement: Digital scale.	—

Secondary

Measure	Time frame
25 (OH)vit D. Timepoint: Before intervention, after intervention. Method of measurement: ELISA.;Serum Ferritin. Timepoint: Before intervention, after intervention. Method of measurement: ELISA.;Serum iron. Timepoint: Before intervention, after intervention. Method of measurement: Spectrophotometry.;Albumin. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Serum transferrin. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Serum Zinc. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Serum IGF-1. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Anthropometric indices (weight, Height, BMI). Timepoint: Before intervention, after intervention. Method of measurement: Digital scales.	—

Measure

Time frame

25 (OH)vit D. Timepoint: Before intervention, after intervention. Method of measurement: ELISA.;Serum Ferritin. Timepoint: Before intervention, after intervention. Method of measurement: ELISA.;Serum iron. Timepoint: Before intervention, after intervention. Method of measurement: Spectrophotometry.;Albumin. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Serum transferrin. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Serum Zinc. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Serum IGF-1. Timepoint: Before intervention, after intervention. Method of measurement: Laboratory measurement.;Anthropometric indices (weight, Height, BMI). Timepoint: Before intervention, after intervention. Method of measurement: Digital scales.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Aqaeinezhad

Shiraz University of Medical Sciences

aqaeinezhad@sums.ac.ir+98 71 3725 1001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026