osteoporosis. Osteoporosis with current pathological fracture
Conditions
Interventions
Intervention 1: Intervention group: 4 mg Zolendronic acid IV infusion in the first post transplant week. Intervention 2: Control group: 250 cc normal saline IV infusion in the first post transplant we
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: age:> 18 years, and receiving cadaveric kidney transplant
Exclusion criteria
Exclusion criteria: history of previous parathyroidectomy history of hyperthyroidism severe hyperparathyroidism (> 800 ng/ml) immobilization GFR less than 35 cc/min or serum creatinine more than 2 mg/dl in post-transplant period treatment with corticosteroids for more than 3 months before transplantation treatment with calcitonin and bisphosphonates 25 (OH) vitamin D3 level less than 10 ng/ml at the beginning of the study post- transplant hypercalcemia or hypocalcemia recieving calcitriol in post transplant period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Trabecular bone score (TBS). Timepoint: 1- in the first post transplant month 2- 6 months after transplant. Method of measurement: Bone mass densitometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahrokh Ezatzadegan Jahromi
Shiraz University of Medical Sciences
Outcome results
None listed