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Effect of two drugs, propofol and fentanyl in controlling emergence agitation following anesthesia with sevoflurane gas

Comparison the effect of two drugs, propofol and fentanyl in controlling emergence agitation of 2 to10 years old children following general anesthesia with sevoflurane

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181130041804N1
Enrollment
50
Registered
2019-01-23
Start date
2018-12-31
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

agitation due to sevoflurane gas. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention 1: Intervention Group: Receive 0.5mg/kg Propofol drug after agitation. Intervention 2: Control Group: Recieve 0.5mcg/kg Fentanyl drug after agitation.

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children aged 2 to 10 years old Class one or two of ASA Children under general anesthesia with sevoflurane

Exclusion criteria

Exclusion criteria: Children with growth retardation Children with psychological diseases Children with neurological disease Children with abnormal airway Irritable children

Design outcomes

Primary

MeasureTime frame
Agitation Score. Timepoint: 5 ,10 ,15 ,20 minute after the treatment of Agitation. Method of measurement: RASS (Richmond agitation sedation scale).

Secondary

MeasureTime frame
Vomiting. Timepoint: 5,10,15,20 minutes after injection of propofol or fentanyl. Method of measurement: In the form of positive or Negative by watching and reporting the caregiver.;Nausea. Timepoint: 5,10,15,20 minutes after injection of propofol or fentanyl. Method of measurement: In the form of positive or Negative by watching and reporting the caregiver.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Amini

Sanandaj University of Medical Sciences

arash.amini@muk.ac.ir+98 87 3356 5863

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026