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Effect of SLN containing finasteride on anderogenic alopecia

Comparison of the effectiveness of SLN containing finasteride and finasteride tablets in androgenic alopecia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181128041780N1
Enrollment
50
Registered
2019-06-30
Start date
2018-11-30
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anderogenic alopecia. Androgenic alopecia

Interventions

Intervention 1: Intervention group: In the first group, 5% localized minoxidil twice a day, any time 1 cc with a 0.1% finasteride topical form, as SLN, once a day, any time 1 cc. Intervention 2: Contr

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Men with Androgenic Alopecia Based on Hamilton's Criteria. Stage 2-4 Completing the consent form

Exclusion criteria

Exclusion criteria: No endocrine disease (diabetes), thyroid disorders, systemic diseases including lupus, other cases, including arthritis and cicatrisil (associated with scar), history of skin or systemic malignancy, psychiatric disorders, skin disorders Head skulls other than those with AGASerious Cardiovascular Diseases, Kidney Disease, Liver Disease No use of zinc and iron supplements, malnutrition, iron deficiency anemia Non-use of medications leads to hair loss, including anti-hypertensive and anti-inflammatory drugs, NSAIDs No history of alcohol consumption or substance abuse No history of finasteride in the last 6 months and minoxidil in the past month No history of drug hypersensitivity, breast disorders, surgical history for the treatment of hair loss

Design outcomes

Primary

MeasureTime frame
The number of hair from short hair in 1 cm square in the area of assessment in the Vertex hairless part. Timepoint: At the beginning of the work and weeks 8, 16 and 24. Method of measurement: Using the computer scan obtained from macrophotography images of the marked area, it is evaluated for hair growth.

Secondary

MeasureTime frame
1- Evaluation of the frequency of local skin complications including: erythema-burning-itchy-folliculitis-clinical diagnosis by the assessor. Timepoint: At the beginning of the work and weeks 8, 16 and 24. Method of measurement: 1-Measuring erythema and itching and burning with a visual analogue scale and evaluating folliculitis clinically and by assessor.;2. Quality of life assessment. Timepoint: At the beginning of the work and weeks 8, 16 and 24. Method of measurement: 2. Assessing the quality of life ,the basis of the WAA-QOL benchmark.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsama gharaei

Mashhad University of Medical Sciences

gharaeis941@mums.ac.ir+98 51 3882 3255

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026