Inflammatory Bowel Disease (Ulcerative Colitis). Ulcerative colitis
Conditions
Interventions
Intervention 1: Intervention group: Low-FODMAP diet in addition to general recommendations for IBD patients. Firstly, the basal metabolic rate (BMR) of the patients will be calculated using their age,
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age over than 20 and under 60 years Moderate ulcerative colitis (ulcerative colitis diagnosis will be done by a gastroenterologist, using the Mayo score) who are on stable drug therapy. The scores of 6-8 will be considered as moderate UC. BMI 18.5 to 30 kg/m2
Exclusion criteria
Exclusion criteria: Changed in the type or dosage of their drugs over the past month Suffered from other gastrointestinal diseases including cancers and infectious diseases Pregnant or breastfeeding women or those with a decision for pregnancy in the near future Use of antibiotics Consumed pre- or pro-biotic products during the last two months Use tobacco or smoke Hospitalized in the last three months Infection over the past 3 months Suffering from any inflammation-promoting condition Used multi-vitamin and mineral supplements during the past month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota. Timepoint: Before Intervention and 4 weeks later. Method of measurement: PCR Method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation. Timepoint: Before intervention and 4 weeks later. Method of measurement: ELISA kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Milajerdi
Tehran University of Medical Sciences
Outcome results
None listed