Gargling effect of Ketamine and Dexmedetomidine on sore throat

Comparison of Ketamine and Dexmedetomidine on sore throat after induction of anesthesia with Sachinyl Choline in emergency operations

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181126041760N2

Enrollment

Registered

2020-01-23

Start date

2019-02-20

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat after induction of anesthesia with Succinylcholine in emergency procedures. Contusion of throat, initial encounter

Interventions

Intervention 1: Intervention group 1: in this group, 0.25 µg of dexmedetomidine per 100 ml of mixed water will be gargled for 1 minute, 5 minutes before anesthesia. Then the same fluid therapy and sim

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients who are candidates for emergency surgery Emergency surgery under general anesthesia with Sachinyl Choline Patients with ASA Class 1-2 Aged between 18 and 65 years old

Exclusion criteria

Exclusion criteria: The operation lasts more than 2 hours Problem intubation Laryngoscopy more than once Any intraoperative complication including heart rhythm disorders Bleeding more than maximum allowable blood loss (MABL)

Design outcomes

Primary

Measure	Time frame
Postoperative sore throat severity. Timepoint: 0,2,4,12 ,24 hour after operation. Method of measurement: Visual Analog Scale.;Postoperative dry throat. Timepoint: 0,2,4,12 ,24 hour after operation. Method of measurement: questionaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHouman Teymourian

Shahid Beheshti University of Medical Sciences

houman72625@yahoo.com+98 21 2274 1174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026