Comparison of the effect of simultaneous administration of oxytocin with Foley catheter with co-administration of misoprostol and Foley catheter on cervical preparation and duration of labor

Comparison of the effect of simultaneous administration of oxytocin with Foley catheter with co-administration of misoprostol and Foley catheter on cervical preparation and duration of labor in extended pregnancies.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181123041731N2

Enrollment

Registered

2019-06-26

Start date

2019-06-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

extended pregnancies. Obstructed labor, unspecified

Interventions

Intervention 1: Intervention group: immediately after placing the Foley catheter, administration of oxytocin with dosage of 2 milliunits/min begins and 2 milliunits are added every 20 minutes up to re

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Alive singleton pregnancy Gestational age of equal to or greater than 40 weeks Cephalic presentation Absence of fetal anomaly Weight estimate of the fetus is less than 4500 grams Bishop Score of less than 4 Mother's age is greater than 18 Absence of parity of over 5 Absence of medical illnesses such as diabetes and high blood pressure

Exclusion criteria

Exclusion criteria: Placental abruption Chorioamnionitis Rupture of the membrane before the catheter is excreted Previous Cesarean section Gestational diabetes Placenta Previa and any type of contraindication for vaginal bleeding

Design outcomes

Primary

Measure	Time frame
Duration of reaching Bishop Score of 7 (the cervix is ready). Timepoint: 4 every 4 hours. Method of measurement: Internal examination.	—

Secondary

Measure	Time frame
Duration of delivery. Timepoint: From admission to delivery. Method of measurement: Based on patient's file.;Delivery method. Timepoint: At the time of delivery. Method of measurement: Based on the type of delivery which is recorded in the patient's file.;Labor complications including tachysystole (more than 5 contractions in 10 minutes), bleeding after delivery. Timepoint: After delivery. Method of measurement: Clinical observation.	—

Measure

Time frame

Duration of delivery. Timepoint: From admission to delivery. Method of measurement: Based on patient's file.;Delivery method. Timepoint: At the time of delivery. Method of measurement: Based on the type of delivery which is recorded in the patient's file.;Labor complications including tachysystole (more than 5 contractions in 10 minutes), bleeding after delivery. Timepoint: After delivery. Method of measurement: Clinical observation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Rakhshani Far

Mashhad University of Medical Sciences

rakhshanifm951@mums.ac.ir+98 51 3801 2477

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026